More IST-3 comment: lets use a rod and reel instead of a drift net

A nicely written comment on IST-3 which is similar in conclusion to my original post (i.e. this is a rubbish study that adds nothing and contains badly orchestrated smoke and mirrors, but there probably is a group who will benefit, we just don’t know exactly who they are yet, and future research shouldn’t cast the net wider but should focus): http://sphemerg.ca/content/clinical/issue-international-stroke-trial-3

Advertisements

About dreapadoir

Emergency Physician, author of http://underneathEM.com Emergency Medicine blog, photographer at http://www.dreapadoir.com
This entry was posted in Discussions and rants, Medical Musings. Bookmark the permalink.

4 Responses to More IST-3 comment: lets use a rod and reel instead of a drift net

  1. Sameer says:

    This trial is definitely not fulfilled major expected results, but some points are very interesting that,
    1. Bleeding risk is equal with 4.5-6 hr vs 80yrs with stroke and patients coming in 3hours with >16 NIHSS.
    LOOKING INTO ALL OFF LEVEL USE IF THIS TRIAL IS GIVING 29% beneficial results THEN I DON’T THINK THERE IS ANY BETTER OPTION IS AVAILABLE FOR THESE TYPE PATIENTS.

    REGARDS
    SAMEER

  2. Sameer says:

    Hi Sameer you are very right. I am convinced with you.

  3. Pedrinha says:

    I just don’t understand where the 29% beneficial results are , could you tell ?
    Thanks

    • dreapadoir says:

      It has been already pointed out by many authors more eminent than me that the conclusions trumpeted in the abstract by the authors of IST3 bear no resemblance to the data they actually collected and analysed. I have no explanation, merely extreme concerns about how thus study is being touted.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s